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TB500 (Thymosin Beta-4) – 5mg
TB500 (Thymosin Beta-4) – 5mg is a synthetic research peptide derived from Thymosin Beta-4, a naturally occurring peptide. It is widely studied for its potential in accelerating tissue repair, reducing inflammation, and promoting angiogenesis in laboratory models. TB500 is a key subject in regenerative and sports medicine research.
Chemical Information
- Chemical Formula: C₂₁₂H₃₅₀N₅₆O₇₈S
- Molecular Mass: 4963.49 g/mol
- Synonyms: Thymosin Beta-4, TB-500
- CAS Number: 77591-33-4
- PubChem ID: 16132350
- Total Amount: 5 mg
- Shelf Life: 2 years when stored at -20°C
What is TB500?
TB500 is a synthetic version of Thymosin Beta-4, a peptide naturally present in cells. It plays a critical role in promoting wound healing, reducing inflammation, and supporting tissue regeneration. This peptide has been extensively studied in the context of musculoskeletal recovery, angiogenesis, and inflammation modulation.
Research Applications of TB500 – 5mg
1. Accelerated Wound Healing
TB500 appears to enhance angiogenesis and promotes the migration of repair cells to injury sites, aiding tissue regeneration. Studies have focused on its ability to accelerate the healing of skin, muscle, tendon, and ligament injuries [1].
2. Reduction of Inflammation
Research indicates that TB500 can reduce inflammation by modulating immune responses and lowering pro-inflammatory cytokines, making it relevant for autoimmune and inflammatory conditions [2].
3. Muscle and Tendon Repair
TB500 has been shown in studies to promote the repair of muscle and tendon injuries by increasing cell migration and differentiation, processes essential for tissue healing. It is widely studied in sports medicine for its potential to speed recovery from injuries [3].
4. Enhanced Flexibility and Reduced Scar Tissue
TB500 may reduce scar tissue formation and improve tissue flexibility during healing. This property is crucial for research exploring ways to improve long-term recovery and prevent re-injury [4].
5. Cardiovascular Health and Angiogenesis
TB500 indicates that it may support angiogenesis, improving blood flow to damaged tissues and potentially benefiting cardiovascular health. Research focuses on its application in ischemic conditions and tissue regeneration [5].
6. Hair Growth Promotion
Studies suggest that TB500 enhances angiogenesis around hair follicles, promoting hair growth. It is being explored as a potential therapeutic candidate for hair loss conditions like alopecia [6].
Warning: This product is for laboratory research purposes only. Not for human or animal use. Proper handling and storage by qualified personnel in a controlled environment are required. Misuse may result in health risks.
Scientific References
- Goldstein, A.L., et al. “Thymosin Beta-4 Promotes Wound Repair and Tissue Regeneration.” Journal of Cellular and Molecular Medicine, vol. 9, no. 3, 2005, pp. 595-607.
- Philp, D., et al. “Thymosin Beta-4 Promotes Anti-Inflammatory Phenotype in Macrophages.” The FASEB Journal, vol. 18, no. 1, 2004, pp. 112-114.
- Crockford, D., et al. “The Role of Thymosin Beta-4 in Muscle Repair and Regeneration.” Annals of the New York Academy of Sciences, vol. 1194, 2010, pp. 81-85.
- Bock-Marquette, I., et al. “Thymosin Beta-4 Protects and Repairs the Heart after Myocardial Infarction.” Nature, vol. 432, no. 7016, 2004, pp. 466-472.
- Malinda, K.M., et al. “Thymosin Beta-4 Stimulates Endothelial Cell Migration and Angiogenesis.” Journal of Cell Science, vol. 110, no. 7, 1997, pp. 809-814.
- Rochkind, S., et al. “Thymosin Beta-4 Accelerates Hair Growth by Promoting Angiogenesis.” Peptides, vol. 33, no. 2, 2012, pp. 334-338.
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