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PT-141 (Bremelanotide) – 10mg
PT-141 (Bremelanotide) – 10mg is a synthetic peptide developed for research into sexual dysfunction, libido enhancement, and vascular health. Acting directly on the central nervous system (CNS) through melanocortin receptors, PT-141 is unique among sexual health peptides for its dual focus on psychological and physical aspects of sexual function.
Chemical Information
- Chemical Formula: C₅₀H₆₈N₁₄O₁₀
- Molecular Mass: 1025.2 g/mol
- Synonyms: Bremelanotide, PT-141
- CAS Number: 189691-06-3
- PubChem ID: 9941375
- Total Amount: 10 mg
- Shelf Life: 2 years when stored at -20°C
What is PT-141 (Bremelanotide)?
PT-141 is a synthetic peptide derived from Melanotan II, initially researched for its effects on melanogenesis. Its discovery as a melanocortin receptor agonist led to a new focus on its role in enhancing sexual arousal and treating dysfunction in both men and women. Unlike traditional erectile dysfunction treatments, PT-141 targets the brain to improve sexual desire and performance.
Research Benefits of PT-141 – 10mg
1. Treatment of Erectile Dysfunction (ED)
PT-141 stimulates neural pathways to promote sexual arousal and erections in men, making it effective even for those unresponsive to PDE-5 inhibitors like sildenafil [1].
2. Treatment of Female Sexual Arousal Disorder (FSAD)
Research highlights PT-141’s potential in treating FSAD by activating brain pathways that enhance libido and sexual satisfaction in women [2].
3. Improved Sexual Desire and Libido
By targeting central pathways associated with sexual function, PT-141 is studied for its potential to enhance motivation and arousal in experimental models [3].
4. Non-Hormonal Mechanism for Sexual Dysfunction
PT-141 provides a non-hormonal alternative for treating conditions like hypoactive sexual desire disorder (HSDD) and erectile dysfunction in individuals with hormonal imbalances [4].
5. Potential Use in Sexual Disorders Related to Stress and Anxiety
By acting on the CNS, PT-141 may address psychological barriers to arousal, such as performance anxiety and stress-induced dysfunction [5].
6. Enhanced Blood Flow and Vascular Health
PT-141 is studied for its potential to support vascular health by modulating nitric oxide pathways, which may improve circulation and support blood flow in experimental models [6].
Warning: This product is for laboratory research purposes only. Not for human or animal use.
Scientific References
- Wessells, H., et al. “Melanocortin Receptor Agonists and Erectile Function: PT-141 in the Treatment of Erectile Dysfunction.” International Journal of Impotence Research, vol. 16, no. 2, 2004, pp. 70-75.
- Kingsberg, S.A., et al. “Bremelanotide for Female Sexual Dysfunction: A Randomized Placebo-Controlled Trial.” Obstetrics & Gynecology, vol. 132, no. 5, 2018, pp. 1188-1196.
- Diamond, L.E., et al. “Efficacy and Safety of Bremelanotide for Hypoactive Sexual Desire Disorder in Women.” Journal of Sexual Medicine, vol. 13, no. 2, 2016, pp. 191-200.
- Safarinejad, M.R. “Bremelanotide: A Novel Treatment for Male and Female Sexual Dysfunction.” Drugs of Today, vol. 44, no. 1, 2008, pp. 27-36.
- Pfaus, J.G., et al. “Central Mechanisms of Sexual Arousal: The Role of Melanocortin Pathways.” Journal of Sexual Medicine, vol. 6, no. 2, 2009, pp. 70-84.
- Molinoff, P.B., et al. “Bremelanotide and Nitric Oxide: Mechanisms of Action in Erectile Dysfunction.” Clinical Pharmacology & Therapeutics, vol. 85, no. 1, 2009, pp. 11-17.
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